The Acceava Mono Cassette test provides superior
performance for the diagnosis of Mononucleosis. This simple
procedure provides an answer during the patient visit, enabling you
to deliver improved patient care with a test that fits your
staffing requirements.
Easy to Use
- One product available for both CLIA-Moderate and Waived
labs.
- Walk-away Flexibility / Room Temperature Storage
- Environmentally Friendly Packaging (Minimal Plastic
Waste)
- CLIA Non-waived for Serum, Plasma or Whole Blood
Specimens
- CLIA Waived for Whole Blood Specimens Only
Further Benefits of the Acceava Mono Test
- Cost-Effective Diagnosis of Mononucleosis
- Affordably priced for any setting
- Rapid, flexible procedure reduces office staff hands-on time
and follow-up activities
- Decrease unnecessary use of antibiotics
- Decrease need for ancillary testing
Acceava®
Mono II Dipstick Test
Procedure
Add sample to tube.
- 2 drops of
whole blood from venipuncture or full capillary tube for
fingerstick or
- 1 drop serum or plasma.
Add Buffer. Follow sample with 2 drops of Buffer
solution.
Place Test Strip into Sample
Tube.
Read result in 5 minutes. For full
instructions, see package insert.
Acceava® Mono Cassette Test
Procedure
About Mono
Infectious mononucleosis (commonly called "mono") often produces
symptoms of fever, sore throat, and swollen lymph glands. The name
infectious mononucleosis refers to the appearance of infected white
blood cells, as they appear to have a grossly distorted single
nucleus, together with an increase in the number of
monocytes.1
Mono is caused by Epstein-Barr virus (EBV), which is a member of
the herpesvirus family and one of the most common human viruses. As
many as 95% of adults between 35 and 40 years of age have been
infected with EBV sometime during their lives.1
Mono is sometimes referred to as the "kissing disease" because
transmission of EBV requires contact with the saliva of an infected
person. However, EBV is also found in the saliva of healthy people;
in fact, these people can carry and spread the virus intermittently
for life.2
Diagnosis of mono is based on the evaluation of characteristic
clinical symptoms and serologic changes. Serologic diagnosis of
mono can be based on the detection of heterophile and EBV-specific
antibodies.3-5
References
- Davidsohn I. Serological diagnosis of infectious mononucleosis.
JAMA. 1937;108(4): 289-295.
- Centers for Disease Control. National Center for Infectious
Diseases. Epstein-Barr Virus and Infectious Mononucleosis.
Available at: http://www.cdc.gov/ncidod/diseases/ebv.htm.
Accessed March 24, 2004.
- Evans AS, Niederman JC, Cenabre LC, West B, Richards VA. A
prospective evaluation of heterophile and Epstein-Barr
virus-specific IgM antibody test in clinical and subclinical
infectious mononucleosis: Specificity and sensitivity of the tests
and persistence of antibody. J Infect Dis.
1975;132(5):546-554.
- Fletcher MA, Woolfolk BJ. Immunochemical studies of infectious
mononucleosis. Isolation and characterization of heterophile
antigens from hemoglobin-free stroma. J Immunol.
1971;107(3):842-853.
- Khanna R, Burrows SR, Moss DJ. Immune regulation in
Epstein-Barr virus-associated diseases. Microbiol Rev.
1995;59:387-405